Tickborne BBB Direct Detect 1 day – dPCR
The most sensitive test methodology available for direct detection of Bartonella, Babesia, and Borrelia species (spp). (BBB) pathogens.
People can be exposed to Bartonella, Babesia, and Borrelia through exposure to ticks, fleas, lice, sand flies, and potentially spiders. These vectors can carry multiple pathogens at once, making co-infections common. These stealth pathogens can cause overlapping, persistent symptoms that are often misdiagnosed. Identifying which of these infections are present helps providers tailor treatment more effectively—especially since each requires a different therapeutic approach. Without proper testing, co-infections can be missed, leading to incomplete or ineffective care.
Discover the Power of MosaicDX’s Tickborne BBB Direct Detect
Direct testing is particularly valuable in detecting the current presence of pathogens when antibody responses might be absent or unclear. Many patients with detectable spp. DNA never develop detectable antibodies, while others may only show very low titers. The result is that many patients with current presence of pathogens are missed by both conventional PCR and antibody testing.
Tickborne BBB Direct Detect dPCR, confirms the presence of pathogens by directly detecting genus-level DNA for a broad range of Bartonella, Borrelia, and Babesia species (spp) in whole blood. This approach ensures that less common species are not missed.
Methodology: Indirect Immunuofluorescence Assay (IFA)
Indirect Immunuofluorescence Assay (IFA):
Confirms antibodies against the four most common species of infection based on public research.
A laboratory technique used for detecting and visualizing specific antigens or antibodies in biological samples. It combines the principles of both immunology and fluorescence microscopy to provide highly specific and sensitive results.
When bacteria are present in the body, the immune system creates antibodies that help eliminate them. Test methods, such as IFA determine the level of IgG antibodies circulating in a patient, which can be useful for the diagnosis of Bartonellosis (Bartonella spp infection), “or” for monitoring treatment response.
Bartonella IgG Detect – IFA utilizes authentic cell-cultured clinical isolates for Bartonella species that most commonly affect humans in North America:
- B. henselae
- B. vinsonii
- B. berkhoffii
- B. koehlerae
Serum samples are serially diluted in a sample buffer, and the test results are reported as titers.
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