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Delta-Fraction Tocotrienols contains tocotrienols from annatto beans and is free of tocopherols. Tocotrienols have more powerful antioxidant activity than tocopherols.*
Delta-Fraction Tocotrienols contains delta- and gamma-tocotrienols. Along with tocopherols, tocotrienols are part of the vitamin E family. They are important oil-soluble antioxidants, crucial to the protection of fats, oils, and cell membranes against free radical damage.* Free radicals are reactive oxygen compounds generated by our normal biological processes and by exposure to ultraviolet radiation, pollution, cigarette smoke and other environmental and biological stress factors. High levels of free radicals can break down cell membranes and damage cell DNA.
Tocotrienols may potentially support endothelial functions and overall cardiovascular health in other ways, including supporting healthy levels of thromboxane, adhesion molecules, and C-reactive protein (CRP).* Tocotrienols do not lower plasma coenzyme Q10, but instead increase it.*
Tocotrienols have been shown to strengthen arterial walls, and to support blood flow through arteries )coronary, carotid, and peripheral). Tocotrienolas help prevent the oxidation of LDL cholesterol and some studies suggest that tocotrienols may prevent cholesterol oxidation more effectively than tocopherols. Unlike tocopherols, delta and gamma-tocotrienols also support healthy levels of cholestrol within normal levels, including total and LDL cholestrol. Tocotrienols have an inhibitory effect on HMG-CoA reductase, the liver enzyme that is critical to the rate at which cholesterol is synthesized.
Preliimary research suggests that delta-tocotrienol may potentially enhance insulin function, including insulin sensitivity. Research also suggests that tocotrienols may offer some protection from the sun's ultraviolet radiation, workign synergistically with tocopherols and helpoing preserve tocopherols in skin cells.
A small structural difference between tocopherols and tocotrienols results in distinct functional differences in their antioxidant activities, probably due to differences in how each is incorporated into cellular membranes. Tocopherols, with a saturated side chain that interactis hydrophobically with acyl side chains of emebraine phospholipids, are relatively less able toaccess lipid radicals due to steric hindrance. Tocotrienols, with an unsaturated farnesyl side chain have increased accessibility to lipid radicals and resulting greater antoxidant capacity. Tocopherols also have a significantly longer tail, so they anchor deeply into lipid membranes, whereas tocotrienols anchor less deelpy, allowing them to cross more easily from one membrane to the next. Accoding to Dr. Barrie Tan, delta-tocotrienol is 40-60 times more powerful as an antioxidant than tocopherol.
Tocotrienols occur in many of the same sources as tocopherols, such as oi from rice bran, palm fruit, barley, and wheat germ and both tocopherols and tocotrienols occur in alph, beta, gamma and delta fractions. Palm and rice contain minor amounts of delta-tocotrienol, so Delt-Graction Tocotrienols utiliizes tocotrienols extracted from annatto. Annatto-derived tocotrienols are free of tocopherols and are high in two especially beneficial tocotrienol fractions, delta-tocotrienol and gamma-tocotrienol.
Tocotrienols are well tolerated, with an extensive history of study and safe use. Human consumption of 240 mg/day of tocotrienols for up to two years caused no adverse effects and animal toxicity studies suggest that they are safe at much higher levels.
As a dietary supplement, 1 softgels daily with an evening meal, or as directed by your healthcare practitioner. Higher does (2 or 3 softgels) can be taken in divided doses.
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